Subsequent to enduring the butcher of his whole group in a medication strike imperiled by filthy policemen, the exceptional enemies of opiates operator Nina Manigan (Anne Curtis) needs to assemble the cartels of medications that have a ridiculous move on Manila. Be that as it may, when her new mission is in the most hazardous neighborhood in the city, furious regular folks are turning their group. Gotten between a ruthless medication band and a crowd of wanton natives, their solitary choice is to battle them, moving a claustrophobic road at any given moment toward an ensemble of whole-world destroying viciousness.

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